HUSH Trial

The HUSH trial is trying to find out whether arm function and quality of life in patients with a humeral shaft fracture is better with the cast and brace treatment or with surgery.

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The trial is comparing the two most common treatments for this fracture throughout the UK

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Background

Fractures of the humeral shaft represent 3-5% of all fractures. They occur in a bimodal distribution, typically affecting younger men and older women. The vast majority of humeral shaft fractures occur in patients over 18 years old. There is currently little evidence to support clinicians in their management choices when treating these fractures.

Two of the most common treatments when treating humeral shaft fractures in patients over 18 years old are:

  1. Functional bracing
  2. Surgical fixation

About the trial

To directly compare non-surgical (functional bracing) intervention with a surgical intervention (plate or nail fixation) in the treatment of patients aged 18 years or older with a fracture of the humerus.

We will focus on the treatments’ effectiveness in reducing pain, improving the functionality of the arm and improvements in the patients’ quality of life.

In addition, we will also make a comparison of cost effectiveness.

The HUmeral SHaft fracture trial

A two-phased, multi-centre, prospective, randomised superiority trial.

Trial Participants

All patients 18 and over who present at a trial hospital with this fracture, are eligible to be included in the trial.

Trial Period

3 years

Sample Size

At least 334 adults over 18 years old

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Information for participants

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